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Upingbio
SKU:YP-Ab-11088-100UL
AP2S1 rabbit pAb
AP2S1 rabbit pAb
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- Gene Name: AP2S1 AP17 CLAPS2
- Immunogen: Synthesized peptide derived from human AP2S1 AA range: 26-76
- Specificity: This antibody detects endogenous levels of AP2S1 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
- Function: function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2S1/AP17 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides.,similarity:Belongs to the adaptor complexes small subunit family.,subcellular location:Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.,subunit:Adaptor protein complex 2 (AP-2) is an heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: AP2S1
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