• Glutaredoxin-1 Polyclona Antibody
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YP-Ab-10926-100UL

Glutaredoxin-1 Polyclona Antibody

Glutaredoxin-1 Polyclona Antibody

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  • Gene Name: GLRX GRX
  • Immunogen: Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58
  • Specificity: This antibody detects endogenous levels of human Glutaredoxin-1
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Glutaredoxin-1 (Thioltransferase-1;TTase-1)
  • Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],
  • Function: function:Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.,similarity:Belongs to the glutaredoxin family.,similarity:Contains 1 glutaredoxin domain.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Glutaredoxin-1
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