• LSM2 Polyclona Antibody
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Upingbio

YP-Ab-10904-100UL

LSM2 Polyclona Antibody

LSM2 Polyclona Antibody

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  • Gene Name: LSM2 C6orf28 G7B
  • Immunogen: Synthesized peptide derived from human LSM2 AA range: 33-83
  • Specificity: This antibody detects endogenous levels of human LSM2
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: U6 snRNA-associated Sm-like protein LSm2 (Protein G7b;Small nuclear ribonuclear protein D homolog;snRNP core Sm-like protein Sm-x5)
  • Background: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011],
  • Function: function:Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the snRNP Sm proteins family.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8. LSm subunits form a heteromer with a donut shape.,
  • Species: Human; Mouse; Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: LSM2
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