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Upingbio
SKU:YP-Ab-10900-100UL
APOC1 Polyclona Antibody
APOC1 Polyclona Antibody
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- Gene Name: APOC1 APOC1B
- Immunogen: Synthesized peptide derived from human APOC1 AA range: 1-50
- Specificity: This antibody detects endogenous levels of human APOC1
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Apolipoprotein C-I (Apo-CIB;ApoC-IB;Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB';ApoC-IB')]
- Background: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016],
- Function: function:Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein.,miscellaneous:Apo-CI makes up about 10% of the protein of the VLDL (very low density lipoprotein) and 2% of that of HDL (high density lipoprotein).,online information:Apolipoprotein C1 entry,similarity:Belongs to the apolipoprotein C1 family.,tissue specificity:Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.,
- Species: Human;Rat;Mouse;
- Range: IHC; ELISA
- Protein: APOC1
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