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Upingbio
SKU:YP-Ab-10861-100UL
GRASP Polyclonal Antibody
GRASP Polyclonal Antibody
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- Gene Name: GRASP
- Immunogen: Synthesized peptide derived from human GRASP
- Specificity: This antibody detects endogenous levels of human GRASP
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein)
- Background: This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012],
- Function: function:Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Localized at postsynaptic membranes.,subunit:Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5.,
- Species: Human; Mouse; Rat
- Range: IHC;IF;WB
- Protein: GRASP
- DA: 38kD
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