• TAL1/TAL2 Polyclonal Antibody
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Upingbio

YP-Ab-10853-100UL

TAL1/TAL2 Polyclonal Antibody

TAL1/TAL2 Polyclonal Antibody

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  • Gene Name: TAL1/TAL2
  • Immunogen: Synthesized peptide derived from human TAL1/TAL2
  • Specificity: This antibody detects endogenous levels of human TAL1/TAL2
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Function: alternative products:The splicing pattern is cell-lineage dependent,disease:A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.,domain:The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.,function:Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.,PTM:Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia.,PTM:Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be
  • Species: Human; Mouse; Rat
  • Range: IHC;IF;WB
  • Protein: TAL1/TAL2
  • DA: 35kD
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