• OCT1 Monoclonal Antibody
1 1

Upingbio

YP-Ab-10829-53UL

OCT1 Monoclonal Antibody

OCT1 Monoclonal Antibody

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  • Reaction species: Human;Rat;Mouse;
  • Gene Name: SLC22A1 OCT1
  • Protein name: 45200
  • Molecular weight (DA): 61kD
  • Immunogen: Synthesized peptide derived from human OCT1 Monoclonal Antibody
  • Specificity: This antibody detects endogenous levels of human OCT1 Monoclonal Antibody
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: Solute carrier family 22 member 1 (Organic cation transporter 1;hOCT1)
  • Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008],
  • Function: caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electroge
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