• C1RL Polyclonal Antibody
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Upingbio

YP-Ab-10784-100UL

C1RL Polyclonal Antibody

C1RL Polyclonal Antibody

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  • Gene Name: C1RL
  • Immunogen: Synthesized peptide derived from human C1RL. at AA range: 371-420
  • Specificity: C1RL Polyclonal Antibody detects endogenous levels of C1RL
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000, ELISA 1:10000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)
  • Background: caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.,function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.,induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 CUB domain.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).,
  • Function: caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.,function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.,induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 CUB domain.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: C1RL
  • DA: 53kD
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