• CD66a/b/c Polyclonal Antibody
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Upingbio

YP-Ab-10736-100UL

CD66a/b/c Polyclonal Antibody

CD66a/b/c Polyclonal Antibody

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  • Gene Name: CEACAM1/CEACAM6/CEACAM8
  • Immunogen: Synthetic peptide from human protein at AA range: 130-190
  • Specificity: The antibody detects endogenous CD66a/b/c
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue thre
  • Function: disease:Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders.,disease:Loss or reduced expression is a major event in colorectal carcinogenesis.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: Carcinoembryonic antigen-related cell adhesion molecule 1/6/8 (CD antigen CD66a/b/c)
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