• PDGF-C Polyclonal Antibody
1 1

Upingbio

YP-Ab-10685-100UL

PDGF-C Polyclonal Antibody

PDGF-C Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: PDGFC SCDGF UNQ174/PRO200
  • Immunogen: Synthetic peptide from human protein at AA range: 61-110
  • Specificity: The antibody detects endogenous PDGF-C
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Platelet-derived growth factor C (PDGF-C;Fallotein;Spinal cord-derived growth factor;SCDGF;VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)]
  • Background: platelet derived growth factor C(PDGFC) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010],
  • Function: developmental stage:In the fetal kidney, detected in the developing mesangium, ureteric bud epithelium and the undifferentiated mesenchyme (at protein level).,disease:Downstream target of EWSR1 fusion proteins, contributing to the Ewin family tumors (EFT) malignant phenotype.,disease:Expression increased in patients with uterine leiomyoma (UL).,disease:Predominant PDGF isoform present in patients with proliferative vitreoretinopathy (PVR). Plasmin is the major protease that processes PDGFC in the vitreous of PVR patients.,disease:The medulloblastoma phenotype is associated with PDGFR alpha expression and activation, with PDGFC as a major player in such endogenous autocrine loop.,function:Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three sta
  • Species: Human;Mouse;Rat
  • Range: IHC;IF;ELISA
  • Protein: Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-de
View full details