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Upingbio
SKU:YP-Ab-10683-100UL
CD236 Polyclonal Antibody
CD236 Polyclonal Antibody
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- Gene Name: GYPC GLPC GPC
- Immunogen: Synthetic peptide from human protein at AA range: 11-60
- Specificity: The antibody detects endogenous CD236
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Glycophorin-C (Glycoconnectin;Glycophorin-D;GPD;Glycoprotein beta;PAS-2';Sialoglycoprotein D;CD antigen CD236)
- Background: Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],
- Function: function:This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin C plays an important role in regulating the stability of red cells.,online information:Blood group antigen gene mutation database,online information:Glycophorin C entry,polymorphism:GYPC is responsible for the Gerbich blood group system.,subcellular location:Linked to the membrane via Band 4.1.,tissue specificity:Glycophorin C is expressed in erythrocytes. Glycophorin D is ubiquitous.,
- Species: Human;Rat;Mouse;
- Range: IHC;IF;ELISA
- Protein: Glycophorin-C (Glycoconnectin) (Glycophorin-D) (GPD) (Glycoprotein beta) (PAS-2') (Sialoglycoprotein D) (CD antigen CD236)
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