• Tenascin-R Polyclonal Antibody
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Upingbio

YP-Ab-10663-100UL

Tenascin-R Polyclonal Antibody

Tenascin-R Polyclonal Antibody

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  • Gene Name: TNR
  • Immunogen: Synthetic peptide from human protein at AA range: 1270-1350
  • Specificity: The antibody detects endogenous Tenascin-R
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Tenascin-R (TN-R;Janusin;Restrictin)
  • Background: tenascin R(TNR) Homo sapiens This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of sodium channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013],
  • Function: domain:The EGF-like domains mediate interaction with CNTN1. The fibronectin type-III domains 3-5 mediate interaction with BCAN. The fibronectin type-III domains 1-2 and 7-9 mediate interaction with SCN2B.,function:Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clusteri
  • Species: Human;Mouse;Rat
  • Range: IHC;IF;ELISA
  • Protein: Tenascin-R (TN-R) (Janusin) (Restrictin)
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