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Upingbio
SKU:YP-Ab-10634-100UL
IRS2 Polyclonal Antibody
IRS2 Polyclonal Antibody
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- Gene Name: IRS2
- Immunogen: Synthetic peptide from human protein at AA range: 660-700
- Specificity: The antibody detects endogenous IRS2 protein
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000, ELISA 1:10000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: IRS2
- Background: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008],
- Function: function:May mediate the control of various cellular processes by insulin.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: insulin receptor substrate 2
- DA: 170kD
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