• ZFP91 Polyclonal Antibody
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Upingbio

YP-Ab-10624-100UL

ZFP91 Polyclonal Antibody

ZFP91 Polyclonal Antibody

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  • Gene Name: ZFP91 ZNF757 FKSG11
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ZFP91. AA range:401-450
  • Specificity: The antibody detects endogenous ZFP91 protein
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000, ELISA 1:10000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ZFP91 ZNF757 FKSG11
  • Background: The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010],
  • Function: disease:Overexpressed in most acute myelogenous leukemia (AML) cases (27 over 29).,function:CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.,function:May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis.,online information:Ciliary neurotrophic factor entry,similarity:Belongs to the CNTF family.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Homodimer.,tissue specificity:Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.,tissue specificity:Nervous system.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: zinc finger protein 91 homolog (mouse); ZFP91-CNTF readthrough transcript; ciliary neurotrophic factor
  • DA: 60kD
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