• MST3 (Phospho-Thr18) rabbit pAb
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Upingbio

YP-Ab-10547-100UL

MST3 (Phospho-Thr18) rabbit pAb

MST3 (Phospho-Thr18) rabbit pAb

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  • Gene Name: STK24 MST3 STK3
  • Immunogen: Synthesized peptide derived from human MST3 (Phospho-Thr18)
  • Specificity: This antibody detects endogenous levels of MST3 (Phospho-Thr18) at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.203% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
  • Background: This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Manganese. Only isoform A requires manganese.,function:Protein kinase that act on both serine and threonine residues.,PTM:Autophosphorylated. Isoform B is activated by phosphorylation by PKA.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: MST3 (Phospho-Thr18)
  • DA: 50kD
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