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SKU:YP-Ab-10527-100UL
CRMP-1 (Phospho-Tyr504) rabbit pAb
CRMP-1 (Phospho-Tyr504) rabbit pAb
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- Gene Name: CRMP1 DPYSL1 ULIP3
- Immunogen: Synthesized peptide derived from human CRMP-1 (Phospho-Tyr504)
- Specificity: This antibody detects endogenous levels of CRMP-1 (Phospho-Tyr504) at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, and 0.183% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Unc-33-like phosphoprotein 3) (ULIP-3)
- Background: This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],
- Function: function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Associated with centrosomes and the mitotic spindle during metaphase.,subunit:Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5. Interacts with PLXNA1.,tissue specificity:Brain.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: CRMP-1 (Phospho-Tyr504)
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