• PASK (Phospho-Thr1165) rabbit pAb
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Upingbio

YP-Ab-10513-100UL

PASK (Phospho-Thr1165) rabbit pAb

PASK (Phospho-Thr1165) rabbit pAb

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  • Gene Name: PASK KIAA0135
  • Immunogen: Synthesized peptide derived from human PASK (Phospho-Thr1165)
  • Specificity: This antibody detects endogenous levels of PASK (Phospho-Thr1165) at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.169% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)
  • Background: This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by autophosphorylation on Thr-1161 and Thr-1165 and inhibited by the first PAS domain.,PTM:Autophosphorylated on Thr-1161 and Thr-1165.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,tissue specificity:Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: PASK (Phospho-Thr1165)
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