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SKU:YP-Ab-10467-100UL
BLK (Phospho-Tyr389) rabbit pAb
BLK (Phospho-Tyr389) rabbit pAb
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- Gene Name: BLK
- Immunogen: Synthesized peptide derived from human BLK (Phospho-Tyr389)
- Specificity: This antibody detects endogenous levels of BLK (Phospho-Tyr389) at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, and 0.122% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)
- Background: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
- Function: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: BLK (Phospho-Tyr389)
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