• FGR (Phospho-Tyr412) rabbit pAb
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Upingbio

YP-Ab-10454-100UL

FGR (Phospho-Tyr412) rabbit pAb

FGR (Phospho-Tyr412) rabbit pAb

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  • Gene Name: FGR SRC2
  • Immunogen: Synthesized peptide derived from human FGR (Phospho-Tyr412)
  • Specificity: This antibody detects endogenous levels of FGR (Phospho-Tyr412) at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.107% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
  • Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subunit:Binds PTPNS1.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: FGR (Phospho-Tyr412)
  • DA: 60kD
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