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SKU:YP-Ab-10394-100UL
PZR (phospho-Tyr241) rabbit pAb
PZR (phospho-Tyr241) rabbit pAb
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- Gene Name: MPZL1 PZR UNQ849/PRO1787
- Immunogen: Synthesized phosho peptide around human PZR (Tyr241)
- Specificity: This antibody detects endogenous levels of Human Mouse Rat PZR (phospho-Tyr241)
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Myelin protein zero-like protein 1 (Protein zero-related)
- Function: domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.,PTM:N-glycosylated.,PTM:Phosphorylated on tyrosine residues up
- Species: Human;Mouse;Rat
- Range: WB;ELISA;IHC
- Protein: PZR (Tyr241)
- DA: 30kD
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