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Upingbio

SKU:YP-Ab-09123-100UL

KHK rabbit pAb

KHK rabbit pAb

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  • Gene Name: KHK
  • Immunogen: Synthesized peptide derived from human KHK AA range: 102-152
  • Specificity: This antibody detects endogenous levels of KHK at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + D-fructose = ADP + D-fructose 1-phosphate.,caution:Form C has not yet been fully sequenced in its N-terminal (from 1-69).,disease:Defects in KHK are the cause of fructosuria [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.,enzyme regulation:Requires potassium. Inhibition by ADP.,pathway:Carbohydrate metabolism; fructose metabolism.,similarity:Belongs to the carbohydrate kinase pfkB family.,subunit:Dimer of A-A, A-C or C-C.,tissue specificity:Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: KHK
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