• MTMR5 rabbit pAb
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Upingbio

YP-Ab-08951-100UL

MTMR5 rabbit pAb

MTMR5 rabbit pAb

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  • Gene Name: SBF1 MTMR5
  • Immunogen: Synthesized peptide derived from human MTMR5 AA range: 320-370
  • Specificity: This antibody detects endogenous levels of MTMR5 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8. [provided by RefSeq, Dec 2014],
  • Function: function:Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.,similarity:Contains 1 dDENN domain.,similarity:Contains 1 DENN domain.,similarity:Contains 1 GRAM domain.,similarity:Contains 1 myotubularin phosphatase domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 uDENN domain.,subunit:Interacts with the SET domain of MLL/HRX. Interacts with SUV39H1.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: MTMR5
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