• UCKL1 rabbit pAb
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Upingbio

YP-Ab-08943-100UL

UCKL1 rabbit pAb

UCKL1 rabbit pAb

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  • Gene Name: UCKL1 URKL1 F538
  • Immunogen: Synthesized peptide derived from human UCKL1 AA range: 223-273
  • Specificity: This antibody detects endogenous levels of UCKL1 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
  • Function: catalytic activity:ATP + cytidine = ADP + CMP.,catalytic activity:ATP + uridine = ADP + UMP.,function:May contribute to UTP accumulation needed for blast transformation and proliferation.,pathway:Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.,PTM:Ubiquitinated by RNF19B; which induces proteasomal degradation.,similarity:Belongs to the uridine kinase family.,subcellular location:EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.,subunit:Interacts with RNF19B and EBV EBNA3.,tissue specificity:Ubiquitous.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: UCKL1
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