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Upingbio
SKU:YP-Ab-08885-100UL
CCDC6 rabbit pAb
CCDC6 rabbit pAb
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- Gene Name: CCDC6 D10S170 TST1
- Immunogen: Synthesized peptide derived from human CCDC6 AA range: 104-154
- Specificity: This antibody detects endogenous levels of CCDC6 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010],
- Function: disease:A chromosomal aberration involving CCDC6 is a cause of thyroid papillary carcinoma (PACT) [MIM:188550]. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.,domain:The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.,subcellular location:May be a cytoskeletal protein.,tissue specificity:Ubiquitously expressed.,
- Species: Human; Mouse
- Range: WB
- Protein: CCDC6
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