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Upingbio
SKU:YP-Ab-08882-100UL
LOXL3 rabbit pAb
LOXL3 rabbit pAb
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- Gene Name: LOXL3 LOXL
- Immunogen: Synthesized peptide derived from human LOXL3 AA range: 130-180
- Specificity: This antibody detects endogenous levels of LOXL3 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a lysyl oxidase, which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate, spine deformity, and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome. [provided by RefSeq, Sep 2016],
- Function: cofactor:Contains 1 lysine tyrosylquinone.,cofactor:Copper.,PTM:The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.,similarity:Belongs to the lysyl oxidase family.,similarity:Contains 4 SRCR domains.,tissue specificity:Expressed in many tissues, the highest levels among the tissues studied being seen in the placenta, heart, ovary, testis, small intestine and spleen.,
- Species: Human; Mouse
- Range: WB
- Protein: LOXL3
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