• SDPR rabbit pAb
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Upingbio

YP-Ab-08702-100UL

SDPR rabbit pAb

SDPR rabbit pAb

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  • Gene Name: SDPR
  • Immunogen: Synthesized peptide derived from human SDPR AA range: 129-179
  • Specificity: This antibody detects endogenous levels of SDPR at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009],
  • Function: function:May play a role in targeting PRKCA to caveolae.,induction:Up-regulated in asyncronously growing fibroblasts following serum deprivation but not following contact inhibition. Down-regulated during synchronous cell cycle re-entry.,miscellaneous:Binds phosphatidylserine (PS) in a calcium-independent manner. PS-binding is inhibited by phosphotidic acid and phosphatidylinositol. Does not bind phosphatidylcholine.,PTM:Phosphorylated on Ser residues.,PTM:The N-terminus is blocked.,similarity:Belongs to the PTRF/SDPR family.,subcellular location:Colocalizes with CAV1 to caveolae.,subunit:Binds to PRKCA in the presence of phosphatidylserine (By similarity). Interacts with MURC; this augments the transactivation of NPPA by MURC.,tissue specificity:Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: SDPR
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