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SKU:YP-Ab-08619-100UL
VPRBP rabbit pAb
VPRBP rabbit pAb
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- Gene Name: VPRBP DCAF1 KIAA0800 RIP
- Immunogen: Synthesized peptide derived from human VPRBP AA range: 804-854
- Specificity: This antibody detects endogenous levels of VPRBP at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Function: domain:Although not canonical, the WD repeat-like region is related to WD repeats.,function:May act as a receptor for CUL4-DDB1 ubiquitin ligase complex. In case of infection by HIV-1 virus, it is recruited by HIV-1 Vpr, possibly leading to hijack the RBX1-CUL4-DDB2 and arrest the cell cycle in G2 phase.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the VPRBP family.,similarity:Contains 1 LisH domain.,subunit:Interacts with DDB1, suggesting that it may participate to some RBX1-CUL4-DDB2 ubiquitin ligase complex. In case of infection, interacts with HIV-1 virus Vpr protein and forms a ternary complex with HIV-1 Vpr and DDB1.,tissue specificity:Ubiquitously expressed.,
- Species: Human; Mouse
- Range: WB
- Protein: VPRBP
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