• CL12B rabbit pAb
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Upingbio

YP-Ab-08616-100UL

CL12B rabbit pAb

CL12B rabbit pAb

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  • Gene Name: CLEC12B UNQ5782/PRO16089
  • Immunogen: Synthesized peptide derived from human CL12B AA range: 111-161
  • Specificity: This antibody detects endogenous levels of CL12B at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Function: domain:Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.,function:Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.,induction:Down-regulated in activated leukocytes recruited to a site of inflammation.,PTM:Highly N-glycosylated. Glycosylation varies between cell types.,similarity:Contains 1 C-type lectin domain.,subcellular location:Ligand binding leads to internalization.,subunit:Homodimer. Interacts with PTPN6 a
  • Species: Human; Mouse
  • Range: WB
  • Protein: CL12B
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