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Upingbio
SKU:YP-Ab-08587-100UL
EXOC6 rabbit pAb
EXOC6 rabbit pAb
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- Gene Name: EXOC6 SEC15A SEC15L SEC15L1
- Immunogen: Synthesized peptide derived from human EXOC6 AA range: 610-660
- Specificity: This antibody detects endogenous levels of EXOC6 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016],
- Function: function:Component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane.,similarity:Belongs to the SEC15 family.,subunit:The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with CEP110.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: EXOC6
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