• AP1M2 rabbit pAb
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Upingbio

YP-Ab-08553-100UL

AP1M2 rabbit pAb

AP1M2 rabbit pAb

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  • Gene Name: AP1M2
  • Immunogen: Synthesized peptide derived from human AP1M2 AA range: 117-167
  • Specificity: This antibody detects endogenous levels of AP1M2 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
  • Function: function:Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.,PTM:Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.,similarity:Belongs to the adaptor complexes medium subunit family.,similarity:Contains 1 MHD (mu homology) domain.,subcellular location:Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.,subunit:Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or A
  • Species: Human; Mouse
  • Range: WB
  • Protein: AP1M2
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