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SKU:YP-Ab-08447-100UL
LIPA4 rabbit pAb
LIPA4 rabbit pAb
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- Gene Name: PPFIA4 KIAA0897
- Immunogen: Synthesized peptide derived from human LIPA4 AA range: 513-563
- Specificity: This antibody detects endogenous levels of LIPA4 at Human/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008],
- Function: domain:The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.,function:May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.,similarity:Belongs to the liprin family. Liprin-alpha subfamily.,similarity:Contains 3 SAM (sterile alpha motif) domains.,subcellular location:Colocalizes with PTPRF at the cell surface.,subunit:Forms homodimers and heterodimers with liprins-alpha and liprins-beta. Interacts with the second PTPase domain of PTPRD, PTPRF and PTPRS. Binds RIMS1, RIMS2, GIT1, KIF1A and GRIP1.,tiss
- Species: Human;Rat
- Range: WB
- Protein: LIPA4
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