• HEM1 rabbit pAb
1 1

Upingbio

YP-Ab-08412-100UL

HEM1 rabbit pAb

HEM1 rabbit pAb

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: ALAS1 ALAS3 ALASH OK/SW-cl.121
  • Immunogen: Synthesized peptide derived from human HEM1 AA range: 87-137
  • Specificity: This antibody detects endogenous levels of HEM1 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
  • Function: catalytic activity:Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).,cofactor:Pyridoxal phosphate.,miscellaneous:There are two delta-ALA synthetase in vertebrates: an erythroid- specific form and one (housekeeping) which is expressed in all tissues.,pathway:Porphyrin metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.,similarity:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: HEM1
View full details