• NLGNX rabbit pAb
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YP-Ab-08397-100UL

NLGNX rabbit pAb

NLGNX rabbit pAb

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  • Gene Name: NLGN4X KIAA1260 NLGN4 UNQ365/PRO701
  • Immunogen: Synthesized peptide derived from human NLGNX AA range: 601-651
  • Specificity: This antibody detects endogenous levels of NLGNX at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
  • Function: disease:Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2) [MIM:300497]. ASPGX2 is considered to be a form of childhood autism.,disease:Defects in NLGN4X may be the cause of susceptibility to X-linked autism 2 (AUTSX2) [MIM:300495]. AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.,function:Putative neuronal cell surface protein involved in cell-cell-interactions.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subunit:Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain.,tissue specificity:Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancre
  • Species: Human;Rat;Mouse;
  • Range: WB
  • Protein: NLGNX
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