• AHSP rabbit pAb
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YP-Ab-08336-100UL

AHSP rabbit pAb

AHSP rabbit pAb

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  • Gene Name: AHSP EDRF ERAF
  • Immunogen: Synthesized peptide derived from human AHSP AA range: 1-51
  • Specificity: This antibody detects endogenous levels of AHSP at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1：50-200. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
  • Function: function:Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.,induction:By GATA-1 during erythroid maturation.,similarity:Belongs to the AHSP family.,subunit:Monomer. Forms an heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin nor alpha(2)beta(2) hemoglobin A.,tissue specificity:Expressed in blood and bone marrow.,
  • Species: Human; Mouse
  • Range: IHC;IF
  • Protein: AHSP
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