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Upingbio
SKU:YP-Ab-08296-100UL
FOXP4 rabbit pAb
FOXP4 rabbit pAb
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- Gene Name: FOXP4 FKHLA
- Immunogen: Synthesized peptide derived from human FOXP4 AA range: 307-357
- Specificity: This antibody detects endogenous levels of FOXP4 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008],
- Function: domain:The leucine-zipper is required for dimerization and transcriptional repression.,function:Transcriptional repressor that represses lung-specific expression.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Forms homodimers and heterodimers with FOXP1 and FOXP2. Dimerization is required for DNA-binding.,
- Species: Human; Mouse
- Range: WB
- Protein: FOXP4
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