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Upingbio
SKU:YP-Ab-08236-100UL
PANK4 rabbit pAb
PANK4 rabbit pAb
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- Gene Name: PANK4
- Immunogen: Synthesized peptide derived from human PANK4 AA range: 8-58
- Specificity: This antibody detects endogenous levels of PANK4 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.351% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Pantothenate kinase 4 (hPanK4) (EC 2.7.1.33) (Pantothenic acid kinase 4)
- Background: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008],
- Function: catalytic activity:ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.,enzyme regulation:Regulated by feedback inhibition by CoA and its thioesters.,function:Plays a role in the physiological regulation of the intracellular CoA concentration.,pathway:Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 1/5.,similarity:Belongs to the type II pantothenate kinase family.,subunit:Interacts with PKM2.,tissue specificity:Ubiquitously expressed with higher expression in the muscle.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: PANK4
- DA: 85kD
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