• TRPV2 rabbit pAb
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YP-Ab-08190-100UL

TRPV2 rabbit pAb

TRPV2 rabbit pAb

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  • Gene Name: TRPV2 VRL
  • Immunogen: Synthesized peptide derived from human TRPV2 AA range: 493-543
  • Specificity: This antibody detects endogenous levels of TRPV2 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.305% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000; IF/ICC 1:100-500;IP 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)
  • Background: This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008],
  • Function: function:Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.,PTM:N-glycosylated.,PTM:Phosphorylated by PKA.,similarity:Belongs to the transient receptor family. TrpV subfamily.,similarity:Contains 6 ANK repeats.,subcellular location:Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homotetramer (Probable). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with RGA.,
  • Species: Human; Mouse;Rat
  • Range: WB; IF;IP
  • Protein: TRPV2
  • DA: 85kD
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