1
/
of
1
Upingbio
SKU:YP-Ab-08175-100UL
RUBIC rabbit pAb
RUBIC rabbit pAb
Regular price
$0.00 USD
Regular price
Sale price
$0.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
- Gene Name: KIAA0226
- Immunogen: Synthesized peptide derived from human RUBIC AA range: 868-918
- Specificity: This antibody detects endogenous levels of RUBIC at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.290% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Run domain Beclin-1 interacting and cystein-rich containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron)
- Background: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
- Function: similarity:Contains 1 RUN domain.,
- Species: Human; Mouse
- Range: WB
- Protein: RUBIC
- DA: 105kD
Share
