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Upingbio
SKU:YP-Ab-08150-100UL
IREB2 rabbit pAb
IREB2 rabbit pAb
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- Gene Name: IREB2
- Immunogen: Synthesized peptide derived from human IREB2 AA range: 702-752
- Specificity: This antibody detects endogenous levels of IREB2 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.265% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2)
- Function: cofactor:Binds 1 4Fe-4S cluster per subunit.,function:Binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.,similarity:Belongs to the aconitase/IPM isomerase family.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: IREB2
- DA: 105kD
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