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Upingbio
SKU:YP-Ab-08149-100UL
IQEC1 rabbit pAb
IQEC1 rabbit pAb
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- Gene Name: IQSEC1 ARFGEP100 BRAG2 KIAA0763
- Immunogen: Synthesized peptide derived from human IQEC1 AA range: 693-743
- Specificity: This antibody detects endogenous levels of IQEC1 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.264% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein)
- Function: function:In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.,similarity:Belongs to the BRAG family.,similarity:Contains 1 IQ domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:At steady state, may be preferentially cytosolic.,subunit:Interacts with ARF6.,tissue specificity:Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.,
- Species: Human; Mouse
- Range: WB
- Protein: IQEC1
- DA: 105kD
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