• INT4 rabbit pAb
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Upingbio

YP-Ab-08147-100UL

INT4 rabbit pAb

INT4 rabbit pAb

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  • Gene Name: INTS4 MSTP093
  • Immunogen: Synthesized peptide derived from human INT4 AA range: 10-60
  • Specificity: This antibody detects endogenous levels of INT4 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.262% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Integrator complex subunit 4 (Int4)
  • Background: INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008],
  • Function: function:Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.,similarity:Belongs to the Integrator subunit 4 family.,similarity:Contains 8 HEAT repeats.,subunit:Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: INT4
  • DA: 105kD
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