• XYLT1 rabbit pAb
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YP-Ab-08138-100UL

XYLT1 rabbit pAb

XYLT1 rabbit pAb

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  • Gene Name: XYLT1 XT1
  • Immunogen: Synthesized peptide derived from human XYLT1 AA range: 312-362
  • Specificity: This antibody detects endogenous levels of XYLT1 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.253% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I)
  • Background: This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009],
  • Function: catalytic activity:Transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxy group of an acceptor protein substrate.,cofactor:Divalent cations.,function:Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.,miscellaneous:Activity is strongly reduced in seminal plasma of unfertile men.,online information:GlycoGene database,pathway:Glycan metabolism; chondroitin sulfate biosynthesis.,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:Contains 7 disulfide bonds.,PTM:N-glycosylated.,similarity:Belongs to the glycosyltransferase 14 family. XylT subfamily.,subcellular location:Some fraction is also found in the extracellular space together with chond
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: XYLT1
  • DA: 105kD
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