• CSTN2 rabbit pAb
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Upingbio

YP-Ab-08120-100UL

CSTN2 rabbit pAb

CSTN2 rabbit pAb

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  • Gene Name: CLSTN2 CS2
  • Immunogen: Synthesized peptide derived from human CSTN2 AA range: 494-544
  • Specificity: This antibody detects endogenous levels of CSTN2 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.235% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Calsyntenin-2 (Alcadein-gamma) (Alc-gamma)
  • Function: domain:Binds synaptic Ca(2+) with its cytoplasmic domain.,function:May modulate calcium-mediated postsynaptic signals.,PTM:Proteolytically processed under normal cellular conditions. A primary zeta-cleavage generates a large extracellular (soluble) N-terminal domain (sAlc) and a short C-terminal transmembrane fragment (CTF1). A secondary cleavage catalyzed by gamma-secretase within the transmembrane domain releases the beta-Alc-gamma chain in the extracellular milieu and produces an intracellular fragment (AlcICD). This processing is strongly suppressed in the tripartite complex formed with APBA2 and APP, which seems to prevent the association with PSEN1.,similarity:Contains 2 cadherin domains.,subcellular location:Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization.,tissue specificity:Restricted to the bra
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: CSTN2
  • DA: 105kD
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