• SAFB2 rabbit pAb
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Upingbio

YP-Ab-08111-100UL

SAFB2 rabbit pAb

SAFB2 rabbit pAb

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  • Gene Name: SAFB2 KIAA0138
  • Immunogen: Synthesized peptide derived from human SAFB2 AA range: 737-787
  • Specificity: This antibody detects endogenous levels of SAFB2 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.226% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Scaffold attachment factor B2 (SAF-B2)
  • Background: The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016],
  • Function: function:Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RRM (RNA recognition motif) domain.,similarity:Contains 1 SAP domain.,subunit:Interacts with SAFB/SAFB1 and SCAM1.,tissue specificity:Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: SAFB2
  • DA: 105kD
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