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Upingbio
SKU:YP-Ab-08107-100UL
AL2CL rabbit pAb
AL2CL rabbit pAb
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- Gene Name: ALS2CL
- Immunogen: Synthesized peptide derived from human AL2CL AA range: 606-656
- Specificity: This antibody detects endogenous levels of AL2CL at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.222% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ALS2 C-terminal-like protein
- Function: function:Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.,similarity:Contains 1 VPS9 domain.,similarity:Contains 8 MORN repeats.,subcellular location:Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.,subunit:Homodimer. Forms a heteromeric complex with ALS2 (By similarity). Interacts with ALS2 and RAB5A.,tissue specificity:Expressed in heart and kidney.,
- Species: Human; Mouse
- Range: WB
- Protein: AL2CL
- DA: 105kD
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