• FBXW5 rabbit pAb
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Upingbio

YP-Ab-08018-100UL

FBXW5 rabbit pAb

FBXW5 rabbit pAb

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  • Gene Name: FBXW5 FBW5 PP3971
  • Immunogen: Synthesized peptide derived from human FBXW5 AA range: 319-369
  • Specificity: This antibody detects endogenous levels of FBXW5 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.132% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
  • Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008],
  • Function: function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 3 WD repeats.,subunit:Interacts with SKP1A and CUL1.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: FBXW5
  • DA: 60kD
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