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SKU:YP-Ab-07985-100UL
PI51A rabbit pAb
PI51A rabbit pAb
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- Gene Name: PIP5K1A
- Immunogen: Synthesized peptide derived from human PI51A AA range: 270-320
- Specificity: This antibody detects endogenous levels of PI51A at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.99% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)
- Function: catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.,function:Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2.,similarity:Contains 1 PI5K domain.,subcellular location:Associated with the plasma membrane and with internal membranes. Associated with Golgi stacks (By similarity). Detected on RAC1-induced plasma membrane ruffles, and on membrane ruffles induced by platelet-derived growth factor.,subunit:Interacts with ARF1, RAC1, PLD1, PLD2 and JUB.,tissue specificity:Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in brain, lung and liver.,
- Species: Human; Mouse
- Range: WB
- Protein: PI51A
- DA: 60kD
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