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Upingbio
SKU:YP-Ab-07921-100UL
IGHA1 rabbit pAb
IGHA1 rabbit pAb
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- Gene Name: IGHA1
- Immunogen: Synthesized peptide derived from human IGHA1 AA range: 118-168
- Specificity: This antibody detects endogenous levels of IGHA1 at Human
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.35% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Ig alpha-1 chain C region
- Function: disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,
- Species: Human;Rat;Mouse;
- Range: WB
- Protein: IGHA1
- DA: 38kD
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