• KERA rabbit pAb
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YP-Ab-07905-100UL

KERA rabbit pAb

KERA rabbit pAb

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  • Gene Name: KERA SLRR2B
  • Immunogen: Synthesized peptide derived from human KERA AA range: 26-76
  • Specificity: This antibody detects endogenous levels of KERA at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.19% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Keratocan (KTN) (Keratan sulfate proteoglycan keratocan)
  • Background: The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).[provided by RefSeq, May 2010],
  • Function: disease:Defects in KERA are the cause of the autosomal recessive cornea plana 2 (CNA2) [MIM:217300]. In CNA2, the forward convex curvature is flattened, leading to a decrease in refraction, reduced visual activity, extreme hyperopia (usually plus 10 d or more), hazy corneal limbus, opacities in the corneal parenchyma, and marked arcus senilis (often detected at an early age). CNA2 is a rare disorder with a worldwide distribution, but a high prevalence in the Finnish population.,disease:Increased expression in the stroma of keratoconus corneas. Keratoconus is a noninflammatory disease characterized by thinning and scarring of the central portion of the cornea.,function:May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.,PTM:Binds keratan sulfate chains.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Cla
  • Species: Human; Mouse
  • Range: WB
  • Protein: KERA
  • DA: 38kD
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