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Upingbio
SKU:YP-Ab-07885-100UL
GGCT Polyclonal Antibody
GGCT Polyclonal Antibody
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- Gene Name: GGCT C7orf24 CRF21
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: GGCT Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
- Function: catalytic activity:(Gamma-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.,function:Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.,induction:By geranylgeraniol.,similarity:Belongs to the gamma-glutamylcyclotransferase family.,subunit:Homodimer.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Gamma-glutamylcyclotransferase (EC 2.3.2.4) (Cytochrome c-releasing factor 21)
- DA: 20kD
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